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Particle Sciences Expands Extrusion Capabilities

Adds Brabender equipment

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Particle Sciences Inc. (PSI) has added a Brabender Mini-Compounder 12 mm twin-screw extruder, plus an ATR Torque Rheometer with single screw extruder for co-extrusion applications, to its development and production lines.

Mark Mitchnick, PSI’s chief executive officer, said, “The demand for cGMP extrusion is increasing. Needs range from hot melt extrusion for solid oral dosage forms to drug eluting devices. Particle Sciences is the leading CRO in this area having invested heavily in equipment, high potency compound handling infrastructure and proprietary modeling software. While there are several fine extruders on the market, Brabender Pharma has focused their 12 mm on the pharmaceutical development space. Its ease of cleaning, full cGMP compliance and extensive data capture capabilities make it a valuable addition to rapid product development efforts.”  

Kevin Van Allen, Brabender Pharma’s vice president of sales and marketing, said, “Particle Sciences is an innovative leader in pharmaceutical extrusion and we are very pleased to be working with them. With the placement of the Mini-Compounder at Particle Sciences, Brabender Pharma clients will now have a U.S. site for evaluation and development of their APIs from early stage and into cGMP production, including highly potent compounds. As pharmaceutical extrusion processes are continually being refined, we feel that the 12 mm Mini-Compounder plus added co-extrusion capabilities will give PSI a world of future product development possibilities.”

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